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  5. What is a Case Control Study?

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  6. Statistical analyses of case-control studies

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COMMENTS

  1. Study Design 101: Case Control Study

    A case-control study was conducted to investigate if exposure to zinc oxide is a more effective skin cancer prevention measure. The study involved comparing a group of former lifeguards that had developed cancer on their cheeks and noses (cases) to a group of lifeguards without this type of cancer (controls) and assess their prior exposure to ...

  2. PDF Design and Analysis of Case-Control Studies

    Analysis of Case-Control Studies The odds ratio (OR) is used in case-control studies to estimate the strength of the association between exposure and outcome. Note that it is not possible to estimate the incidence of disease from a case-control study unless the study is population based and all cases in a defined population are obtained.

  3. Case Control Studies

    A case-control study is a type of observational study commonly used to look at factors associated with diseases or outcomes.[1] The case-control study starts with a group of cases, which are the individuals who have the outcome of interest. The researcher then tries to construct a second group of individuals called the controls, who are similar to the case individuals but do not have the ...

  4. What Is a Case-Control Study?

    A case-control study is an experimental design that compares a group of participants possessing a condition of interest to a very similar group lacking that condition. Here, the participants possessing the attribute of study, such as a disease, are called the "case," and those without it are the "control." ...

  5. Case Control Studies

    A case-control study is a type of observational study commonly used to look at factors associated with diseases or outcomes. The case-control study starts with a group of cases, which are the individuals who have the outcome of interest. The researcher then tries to construct a second group of indiv …

  6. Design and data analysis case-controlled study in clinical research

    Case-control studies look back in time to compare "what happened" in each group to determine the relationship between the risk factor and disease. The case-control study has important advantages, including cost and ease of deployment. ... (73.30%). In this example, large number of false positives and few false negatives indicate the test ...

  7. A Practical Overview of Case-Control Studies in Clinical Practice

    Case-control studies are one of the major observational study designs for performing clinical research. The advantages of these study designs over other study designs are that they are relatively quick to perform, economical, and easy to design and implement. Case-control studies are particularly appropriate for studying disease outbreaks, rare diseases, or outcomes of interest. This article ...

  8. Case-control study: Design, measures, classic example

    The principal measure of a case-control study is the odds ratio, defined as the ratio of the odds of a given exposure in the case group compared to the odds of a given exposure in the control group. 1 This represents the odds of an outcome occurring with a given exposure, compared to the odds of an outcome occurring in the absence of that ...

  9. Introduction to study designs

    Selection bias in case-control studies Selection bias is a particular problem inherent in case-control studies, where it gives rise to non-comparability between cases and controls. Selection bias in case control studies may occur when: 'cases (or controls) are included in (or excluded from) a study because of some characteristic they exhibit ...

  10. A Practical Overview of Case-Control Studies in Clinical Practice

    The case-control study can be subcategorized into four different subtypes based on how the control group is selected and when the cases develop the disease of interest as described in the following sections. Nested Case-Control Study When a case-control study is performed within a cohort study, it is called a nested case-control study. In a ...